COPD Vs Asthma

Chronic obstructive pulmonary disease (COPD) is a chronic inflammatory lung disease that causes obstructed airflow from the lungs. Symptoms include breathing difficulty, cough, mucus (sputum) production and wheezing.

Asthma is a condition in which your airways narrow and swell and may produce extra mucus. This can make breathing difficult and trigger coughing, a whistling sound (wheezing) when you breathe out and shortness of breath. 

1. Age of onsetMiddle age, usually >40 years. Any Age
2. Smoking HistoryCommon, >20 packs yearsMay or not be present
3. Allergy UncommonCommon — Rhinitis, Eczema,Eosinophilia
4. Family HistoryNot Common Common
5. Cardinal features Cough, Expectoration & DyspneaDyspnea, Cough, Wheeze & Chest Tightness
6.Sputum Often Copious Infrequent
7.Symptom free periodIt is chronic & progressive without any symptom free period. There is recurrent attack but the patient is usually symptom free in between attacks. In Chronic Bronchial Asthma, the features may be persistent.
8.Dyspnea Progressive, Persistent (with exacerbation) Intermittent & variable, vary from day to day & peak at night & in early morning
9.Spirometry Airway obstruction is irreversible. Airway obstruction is reversible.
10.Durnal variation of PEFR Less More
11.Sputum MicroscopyIncreased neutrophil & helper T lymphocyteIncreased Eosinophil & Cytotoxic T lymphocyte
12.Bronchodilator Response May not be satisfactoryUsually satisfactory
13.Airway Hyper responsivenessAbsent in 50% casesPresent
14. Destruction of Lung Parenchyma Common Uncommon

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